Istanbul heavyweights Fenerbahçe bid farewell to UEFA Europa League late Thursday, losing 2-1 to Macedonia's Vardar.
Vardar had a decisive win against the yellow canaries in the second match of the Europa League qualifying round.
The Macedonian club advanced to the group stage thanks to a 4-1 win.
Vardar had also beaten Fenerbahçe in the first leg in Macedonia 2-0.