Yeşim Çetir, 26, a patient of Italian surgeon Paolo Macchiarini, who was accused of misconduct after claiming to have carried out groundbreaking synthetic organ transplant work, has died, her father said Tuesday.Macchiarini performed two synthetic trachea transplants on Çetir in Stockholm in 2012 and 2013, but she suffered brutal complications until her death.Macchiarini operated on eight patients between 2011 and 2014, three of them at the prestigious Stockholm-based Karolinska Institute, which selects the winners of the Nobel Prize in medicine.Only one of the patients survived after having a synthetic trachea, designed and implanted by Macchiarini, surgically removed in Russia in 2014.