Air raid sirens rang out across Israel as Iran launched a missile attack on the country.

The rumble of explosions could be heard throughout Jerusalem, and Israeli TV stations showed plumes of smoke rising in Tel Aviv after an apparent missile strike. There were no immediate reports of casualties.

The army said dozens of missiles were launched.

The army has ordered residents across the country to move into bomb shelters.

Israel's firefighting service said its teams were responding to several "major" incidents resulting from an Iranian missile attack, including efforts to rescue people trapped in a high-rise building.

"Firefighting crews are handling several major incidents, mainly in the Dan region" around Tel Aviv, a statement said, adding that "firefighters are working in a high-rise building to rescue trapped individuals and extinguish a fire, as well as responding to two additional destruction sites."

Israel launched blistering attacks on the heart of Iran's nuclear and military structure Friday, deploying warplanes and drones previously smuggled into the country to attack key facilities and kill top generals and scientists.

The ongoing military and intelligence operation raised the potential for all-out war between the countries and propelled the region, already on edge, into even greater upheaval.

Iran quickly retaliated by sending a swarm of drones at Israel, and Supreme Leader Ayatollah Ali Khamenei warned of "severe punishment.” Iran had been censured by the U.N.’s atomic watchdog a day earlier for not complying with obligations meant to prevent it from developing a nuclear weapon.

Israel had long threatened such a strike, and successive American administrations had sought to prevent it, fearing it would ignite a wider conflict across the Middle East and possibly be ineffective at destroying Iran’s dispersed and hardened nuclear program.