Canada is just one win away from a historic return to the FIFA World Cup after 36 years following a 2-0 victory over El Salvador in the qualifiers Wednesday.
The United States, the traditional continental powerhouse, also reignited its qualification campaign with victory against Honduras.
Second-half goals from Atiba Hutchinson, who plays for Turkish Süper Lig giant Beşiktaş, and Jonathan David gave Canada a deserved victory in San Salvador and left their side leading the CONCACAF qualifying standings with 25 points from 11 games.
Although Canada's qualification for Qatar is not mathematically certain, it would require a freak sequence of results for it to fail to qualify for a first World Cup since the 1986 finals in Mexico.
The Canadians lead the standings by four points with three games remaining, all to be played next month. A win over Costa Rica in their next game on March 24 would seal Canada's place in Qatar.
Elsewhere on Wednesday, the USA cruised to a 3-0 win over Honduras in a game played in sub-zero temperatures in St. Paul, Minnesota.
Two Honduras players were substituted at half-time due to the extreme weather conditions at the Allianz Field.
Players from both teams took to the field with multiple layers of clothing, with some opting for balaclavas in addition to gloves and thermal jerseys.
Jamaican referee Oshane Nation also wore a balaclava and gloves throughout.
US ices Honduras in big chill
USA coach Gregg Berhalter defended the decision to play in St. Paul, where temperatures for the evening kick-off plunged to around minus 16 degrees Celsius (3 degrees Fahrenheit).
"We provided Honduras and their staff and the referees with warm weather gear, we provided them with headgear and trying to make it a safe environment for them to play," Berhalter said.
"When we go down to those countries and it's 90 degrees (32 degrees Celsius) and it's unbearable humidity and guys are getting dehydrated and cramping up and getting heat exhaustion. That's the nature of our competition.
"When we scheduled this game and this location, you know, you have to go by average temperatures."
Berhalter's side, beaten 2-0 by Canada on Sunday, bounced back to win with goals from Weston McKennie, Walker Zimmerman and Christian Pulisic.
The victory leaves Team USA with 21 points from 11 games, four adrift of Canada.
With three games remaining, the U.S. looks well-positioned to grab one of the three automatic World Cup qualifying berths available for teams from Central America, North America and the Caribbean.
Mexico is in third, level with the USA on 21 points, after battling to a scrappy 1-0 win over Panama in Mexico City on Wednesday.
Mexico's winner in an unconvincing performance at the Azteca Stadium came via Wolves striker Raul Jimenez from the penalty spot.
The team finishing in fourth place faces a play-off against the winner of the Oceania qualifying tournament.
Elsewhere Wednesday, Costa Rica kept its qualifying hopes alive with a 1-0 away win over Jamaica in Kingston.
The victory leaves Costa Rica in fifth with 16 points, just behind Panama (17 points) following its defeat to Mexico.