"This isn't a war against Hamas or any other Palestinian faction," Abbas said in televised remarks. "This is a war against the entire Palestinian people."
Seven Palestinians, including three children, were killed in the Gaza Strip earlier Wednesday by fresh Israeli airstrikes, bringing the total number of Gazans killed since Monday to 75.
At least 300 Gazans have also been injured by Israeli airstrikes over the same period.
On Tuesday, Israel launched a military offensive – dubbed "Operation Protective Edge" – with the stated aim of staunching rocket fire emanating from Gaza.
Israel, meanwhile, has continued to pound the coastal enclave with airstrikes, while ground troops remain massed on the strip's borders in advance of a possible ground assault.
Abbas noted that ongoing Israeli strikes were killing entire Palestinian families.
"We have two families each losing seven members in strikes on their homes," he fumed.
"We have victims as young as six and as old as 70. Were these people firing rockets from inside their homes?" Abbas asked.
He insisted that Israel was not defending itself against rocket fire, but was rather defending its longstanding occupation of Palestinian territory and its policy of unabated settlement building.
NO SAFE PLACE FOR CIVILIANS IN GAZA U.N. SAYS
Palestinian civilians in densely populated Gaza have no place to hide from Israel's military offensive...
WHY HAS HAMAS REJECTED EGYPT'S CEASEFIRE PROPOSAL?
Many international and regional actors in pursuit of a ceasefire in Gaza, which has been under Israeli...
TURKISH AIRLINES HALTS ISRAEL FLIGHTS FOR 24 HOURS
Turkish Airlines spokesman Ali Genç wrote on his twitter account, "Turkish Airlines, considering the...
EGYPT: KERRY CHECKED BY SECURITY AT PRESIDENTIAL PALACE
Egyptian security officers checked U.S. Secretary of State John Kerry and his top aides with a metal...