At least 50 people are missing, feared dead after a massive landslide in a remote province in northeastern Afghanistan on Tuesday, a provincial official said.

At least 25 women and 22 children are among those missing in the landslide in the Khwahan district of Badakhshan province, deputy provincial governor Gul Mohammad Beidar said.

"We have asked Kabul for help and they have said they are sending two helicopters to assist with the rescue operations," Beidar told AFP.

He said there were no accurate figures on casualties but the death toll was feared to be above 50.

"This is a remote area on the border with Tajikistan and the road to this district remains closed for six months of the year," he added, highlighting the challenges facing the relief effort.

Lal Mohammad Ahmadzai, the police spokesman of Badakhshan, confirmed the toll.

"Initial information shows 100 houses have been destroyed in the landslide and 52 people are missing," Ahmadzai told AFP.

Flooding and landslides often occur during the spring rainy season in northern Afghanistan, with flimsy mud houses offering little protection against rising water levels and torrents of mud.

In May last year a landslide triggered by heavy rains buried a village in a remote area of Badakhshan, killing at least 300 people.

The disaster left hundreds of families homeless in the Argu district of the mountainous province which borders Tajikistan, China and Pakistan.