By 2040, 100 people will live on the moon, melting ice for water, 3D-printing homes and tools, eating plants grown in lunar soil, and competing in low-gravity "flying" sports.
To those who mock such talk as science fiction, experts such as Bernard Foing, ambassador of the European Space Agency-driven "Moon Village" scheme, reply the goal is not only reasonable but feasible too.
At a European Planetary Science Congress in Riga this week, Foing spelt out how humanity could gain a permanent foothold on Earth's satellite, and then expand.
He likened it to the growth of the railways, when villages grew around train stations, followed by businesses.
By 2030, there could be an initial lunar settlement of six to 10 pioneers - scientists, technicians and engineers - which could grow to 100 by 2040, he predicted.
"In 2050, you could have a thousand and then... naturally you could envisage to have family" joining crews there, Foing told AFP. Mere decades from now, "there may be the possibility to have children born on the moon," he enthused.
How man can build a life on moon?
Experts argue that the future lies in collaboration between increasingly cash-strapped national space agencies and the private sector, which can profit from selling resources such as moon-derived rocket fuel.
Robotic exploration is already underway, with several moon landers and rovers planned for the coming years.
Woerner told AFP the goal "is to join international efforts and to bridge Earthly borders and crises."
But for those who think the moon offers an escape from an Earth threatened by climate change and nuclear war, physicist Christiane Heinicke warns it is a "tough" life, and not for everyone.
She had spent a year in a mock Mars environment in Hawaii.
"It is completely devoid of any vegetation, all they see is rocks, regolith (loose rocks and dust), and a sky that is different from ours on Earth," she told AFP by email. "Being either inside the habitat or inside a suit means that you're never able to actually feel the moon/planet you're on. You can't feel the wind (if there is any, like on Mars), you don't feel the Sun on your skin, and whatever you touch feels like the inside of your gloves."
Another problem: "You can never escape your crew mates," she said.
But Foing, who himself spent some time in one of the many earthly modules preparing aspirant moon or Mars explorers, is undeterred.
He hopes to visit the village by 2040.
As for his family, "that will depend on the price... The price of the ticket is in the order of 100 million euros. That's now, but in 20 years, the price of the ticket could be 100 times less," he said.
This will depend largely on advances made by commercial moon explorers developing new technologies, boosting demand for lunar resources, or tourism, and driving prices down.
Elon Musk's SpaceX, for example, hopes to send two humans on a trip around the moon in the next few years, and Blue Origin of Amazon founder Jeff Bezos has plans to deliver five tons of cargo to earth's satellite.