Spinner Jomel Warrican claimed five wickets to help the West Indies secure their first Test victory in Pakistan in nearly 35 years on Monday.
The West Indies won the second Test in Multan by 120 runs on day three to draw the series 1-1.
Pakistan triumphed in the first Test by 127 runs, also in Multan.
Warrican finished with nine wickets in the match – 19 in the series – to give the hosts a taste of their own medicine on sharply spinning pitches.
The last time the West Indies won a Test in Pakistan was in Faisalabad in November 1990, having gone winless on their 1997 and 2006 tours.
"We haven't played in Pakistan for a number of years, but we haven't won here in a while, so to come here and do it as a young group is incredible," said West Indian skipper Kraigg Brathwaite.
He praised the performance of star player Warrican, who scored 36 not out in the West Indies' first innings of 163 and took both the man of the match and player of the series awards.
"Apart from his excellent bowling, he always says he's one of the best players of off-spin in the Caribbean, so it's good to see him get some runs along with wickets."
Pakistan skipper Shan Masood defended his side's spin ploy.
"On the first day we were in the position we wanted – even better, maybe, when we had them eight down," he said.
Resuming on 76-4 and chasing 254, Pakistan's hopes of victory rested on Saud Shakeel, but Kevin Sinclair had the left-hander caught in the slips for 13 to further dent the home team's fading chances.
Babar Azam top-scored with 31 while Mohammad Rizwan made 25 as Pakistan were bundled out for 133.
Warrican bowled nightwatchman Kashif Ali with a straighter ball for one, leaving Pakistan in tatters at 76-6.
Rizwan added 39 for the seventh wicket with Salman Ali Agha before Warrican dismissed the latter leg before for 15 and then bowled Rizwan to bring the tourists within two wickets of victory.
Gudakesh Motie, who took 2-35, removed Noman Ali for six while Warrican deservedly took the last wicket, bowling Sajid Khan for seven to seal the victory.
The defeat sent Pakistan crashing to ninth and last in the World Test Championship table, while the West Indies finished eighth.
Title-holders Australia face South Africa in the WTC final at Lord's in June.
