Türkiye on Friday confirmed a third ballistic missile fired from Iran was shot down, noting that it was in touch with Iran for incident to be clarified.
"A ballistic munition launched from Iran and entering Turkish airspace was neutralized by NATO air and missile defense assets deployed in the Eastern Mediterranean," the Defense Ministry said in a statement.
It assured all necessary measures were being taken and said Ankara was in touch with Tehran to clarify “all aspects of the incident.”
NATO has again intercepted an Iranian ballistic missile heading towards Türkiye, the alliance’s spokesperson Allison Hart said separately.
"NATO remains vigilant and stands firm in its defense of all allies," Hart said.
It was not immediately clear what was targeted, while Turkish media reported warning alarms sounded earlier on Friday around the Incirlik Air Base in southern Adana province, which also houses U.S. personnel.
The latest interception follows two similar incidents in over a week as fighting between Iran, Israel and the U.S. spills across the region.
Residents of Adana, which lies 10 kilometers (6 miles) from the base, were woken up at 3:25 a.m. (12:25 a.m. GMT) by sirens, which sounded for around five minutes, according to the Ekonomim business news website.
It said a red alert sounded at the base.
Several people posted mobile phone footage on social media of a fast-moving object that appeared to be on fire moving through the night sky as police and ambulance sirens wailed through the streets, it said.
Defense news platform SavunmaSanayiST said the objects were "believed to be fragments from a third ballistic missile" or from the interceptor, which had entered the atmosphere and burnt up before falling to the ground.
NATO had on Monday confirmed shooting down a second ballistic missile fired from Iran, prompting Ankara to warn Tehran against "provocative steps".
The announcement came shortly after Washington said it was closing down its consulate in Adana, urging all American citizens to leave southeastern Türkiye, which borders Iran to the east.
Later that day, Iran's President Masoud Pezeshkian phoned Recep Tayyip Erdoğan and denied the missile had been fired from Iran.
Since the U.S.-Israeli war against Iran started, Tehran has launched strikes across the Middle East. Türkiye, which has largely remined neutral in the war, had appeared to have been spared.
The Incirlik air base is an important NATO facility that has been used by U.S. troops for decades, but which also hosts military personnel, including from Spain and Poland, the base's official website says.
U.S. troops are also stationed at Kürecik, another Turkish base in the central Malatya province which houses an early-warning radar system that NATO describes as a "key element" of its missile shield, and which can detect Iranian missile launches.
Although Ankara has categorically denied that the radar data has ever been used to help Israel, its presence has rattled Tehran.
On Tuesday, Türkiye said a Patriot missile defense system was being deployed in Malatya as NATO "strengthened its air and missile defense measures".
