The U.S. and Iran failed to reach a deal to end their war after marathon talks in Islamabad concluded Sunday, casting doubt on a fragile cease-fire.
Each side blamed the other for the failure of the 21-hour negotiations to end fighting that has killed thousands and sent global oil prices soaring since it began over six weeks ago.
"The bad news is that we have not reached an agreement and I think that's bad news for Iran much more than it's bad news for the United States of America," Vice President JD Vance, the head of the U.S. delegation, told reporters shortly before he left Islamabad.
"So we go back to the United States, having not come to an agreement. We've made very clear what our red lines are."
The U.S. and Iranian delegations have left Islamabad to return home, Pakistani sources told Reuters.
Vance said Iran had chosen not to accept American terms, including not to build nuclear weapons.
"We need to see an affirmative commitment that they will not seek a nuclear weapon and they will not seek the tools that would enable them to quickly achieve a nuclear weapon. That is the core goal of the president of the United States, and that's what we've tried to achieve through these negotiations," he added.
The talks in Islamabad, after a cease-fire earlier in the week, were the first direct U.S.-Iranian meeting in more than a decade and the highest-level discussions since the 1979 Islamic Revolution.
Iran's semi-official Tasnim news agency said that "excessive" U.S. demands had hindered reaching an agreement. Other Iranian media said there was agreement on several issues but that the Strait of Hormuz and Iran's nuclear program were the main points of difference.
A spokesperson for Iran's Foreign Ministry said the talks were conducted in an atmosphere of mistrust. "It is natural that we shouldn't have expected to reach agreement in just one session," the spokesperson was quoted as saying by Iranian media.
Pakistan's Foreign Minister Ishaq Dar said it was "imperative" to maintain the two-week cease-fire that was agreed Tuesday as the two sides attempted to wind down a war that began on Feb. 28 with airstrikes by the U.S. and Israel on Iran.
Israeli security cabinet minister, Zeev Elkin, told Army Radio that more talks were still an option, but warned: "The Iranians are playing with fire."
In his brief press conference, Vance did not mention reopening the Strait of Hormuz, a choke point for about 20% of global energy supplies that Tehran has blocked since the war began.
Vance said he had spoken with President Donald Trump as many as a dozen times during the talks. But even as the negotiations continued, Trump said on Saturday that a deal was not entirely necessary.
"We're negotiating. Whether we make a deal or not makes no difference to me, because we've won," he told reporters.
The U.S. delegation included special envoy Steve Witkoff and Trump's son-in-law Jared Kushner. Iran's team included Parliamentary Speaker Mohammad Baqer Ghalibaf and Foreign Minister Abbas Araghchi.
"There were mood swings from the two sides and the temperature went up and down during the meeting," a Pakistani source said in reference to an early round of talks, which began Saturday and carried on overnight.
Before the talks began, a senior Iranian source told Reuters the U.S. had agreed to release frozen assets in Qatar and other foreign banks. A U.S. official denied agreeing to release the money.
As well as the release of assets abroad, Tehran is demanding control of the Strait of Hormuz, payment of war reparations and a cease-fire across the region, including in Lebanon, according to Iranian state TV and officials.
Tehran also wants to collect transit fees in the Strait of Hormuz.
Despite the differences in Islamabad, three supertankers fully laden with oil passed through the Strait of Hormuz Saturday, shipping data showed, in what appeared to be the first vessels to exit the Gulf since the cease-fire deal.
Hundreds of tankers are still stuck in the Gulf, waiting to exit during the two-week cease-fire period.
Trump's stated goals have shifted, but as a minimum, he wants free passage for global shipping through the strait and the crippling of Iran's nuclear enrichment program to ensure it cannot produce an atomic bomb.
Tehran has long denied seeking to build a nuclear weapon.
U.S. ally Israel has also been bombing Tehran-backed armed group Hezbollah in Lebanon and says that the conflict is not part of the Iran-U.S. cease-fire. Iran has insisted that the fighting in Lebanon has to stop.
The Israeli military said it struck Hezbollah rocket launchers overnight between Saturday and Sunday and black smoke could be seen rising in the southern suburbs of the Lebanese capital Beirut Sunday. In Israeli villages near the border, air raid sirens sounded, warning of incoming rocket fire from Lebanon.